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A new drug approved for weight-loss by the U.S. Food and Drug Administration had good results in clinical trials, nonetheless it isn't a panacea for losing weight. It must be used in combination with a low-calorie diet and frequent exercise in order to be effective.

Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err along the side of caution and allow FDA do its job and demand some investigation be done so your public knows the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on their medications.

Researchers discovered that participants taking this drug for a year, lost excess weight within one month and have kept the body weight off through the 56 weeks of the study. Contrave is often a combination of the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which can be made up of multiple active ingredient, that might make them more effective and safer.

Combo-pilling may be the newest fad or even better the newest to come under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is becoming popular will be the fact that at the time of right now there aren't any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be licensed by the FDA.

Seizures can be a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug may also raise blood pressure levels and heartrate, and really should not be used in people who have a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and heart rate and must stop used in patients with uncontrolled high hypertension, along with by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients on the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.


"This may be the first drug I'm mindful of that targets the two appetite and reward centres within the brain," he explained.